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CJC‑1295 is a synthetic analogue of growth hormone‑releasing hormone (GHRH), while Ipamorelin is a selective growth hormone
secretagogue. Together they stimulate the pituitary to release natural human growth hormone (GH) in a pulsatile fashion, mimicking physiological secretion rather than constant supraphysiological exposure.
—
Jump to
Why you should trust us?
Our expertise stems from years of research into peptide therapeutics and an extensive network with reputable
manufacturers. We compile data from peer‑reviewed journals, clinical trials, and verified user
reports to provide balanced, evidence‑based guidance.
All recommendations are grounded in safety considerations and regulatory compliance.
—
What are CJC‑1295 and ipamorelin?
CJC‑1295 (also known as Dalotide): A 29‑amino‑acid peptide that
binds to GHRH receptors, prolonging GH release.
It has a half‑life of up to 8–12 hours when conjugated with albumin, allowing once‑weekly dosing.
Ipamorelin: A pentapeptide (His‑Pro‑Trp‑Gly‑Leu) that selectively activates the
ghrelin receptor subtype, triggering GH release without affecting prolactin or cortisol.
Its half‑life is around 30–45 minutes.
Both peptides are chemically synthesized and available in powder
form for reconstitution before injection.
Why are CJC‑1295 and ipamorelin used together?
The combination exploits synergistic mechanisms:
Amplified GH pulse – Ipamorelin induces a rapid surge; CJC‑1295 sustains it, resulting in higher
peak concentrations.
Balanced hormonal profile – The dual action reduces the risk of
abnormal prolactin or cortisol spikes common with some secretagogues.
Enhanced anabolic effects – Greater GH availability improves protein synthesis, lipolysis, and tissue repair.
Clinical protocols often administer Ipamorelin before bedtime to align with nocturnal GH secretion patterns.
INNERBODY NEWSLETTER
Subscribe for the latest insights on peptide therapy,
dosing strategies, and safety updates delivered directly to your inbox.
—
Ready for the ultimate sleep upgrade?
By mimicking natural nighttime GH release, CJC‑1295 + Ipamorelin can improve deep sleep stages, leading to better recovery,
mood regulation, and metabolic health. Users frequently report increased REM quality and reduced wake‑after‑sleep latency after consistent nightly use.
—
Current therapeutic uses for CJC‑1295 and ipamorelin
Aging & longevity research – Enhancing skin elasticity, bone density,
and mitochondrial function.
Muscle wasting conditions – Treating sarcopenia or cachexia in chronic illnesses.
Rehabilitation – Accelerating recovery from injury or surgery
by promoting tissue repair.
Metabolic disorders – Modulating insulin sensitivity and lipid profiles.
Increasing growth hormone circulation
The peptides increase circulating GH without directly administering it, preserving
the body’s feedback loops. Peak levels rise 3–5 times baseline, but due to pulsatile
release, receptors are less likely to desensitize. This approach
mirrors natural endocrine rhythms better than exogenous
GH injections.
—
Muscle gain and fat loss
Protein synthesis – Elevated GH stimulates IGF‑1 production, which drives
muscle hypertrophy.
Lipolysis – GH enhances hormone‑sensitive lipase activity, accelerating the breakdown of stored triglycerides.
Metabolic rate – Both peptides improve basal metabolic rate by increasing mitochondrial efficiency.
Athletes and bodybuilders often combine these peptides with resistance training
for optimal results.
Other benefits of CJC‑1295 and ipamorelin
Improved immune function – GH supports lymphocyte proliferation.
Cardiovascular health – Enhanced endothelial function and reduced arterial stiffness.
Neuroprotective effects – Potential to mitigate neurodegenerative
processes through IGF‑1 pathways.
Skin rejuvenation – Collagen synthesis is upregulated, reducing fine lines.
Are CJC‑1295 and ipamorelin safe to use?
When sourced from reputable manufacturers and used within recommended dosages, these
peptides are generally well tolerated. Common side effects include mild injection site reactions, transient water retention, or headaches.
Serious adverse events are rare but can occur if misused.
—
Research‑grade vs. pharmaceutical‑grade CJC‑1295 and ipamorelin
Research‑grade – Produced for laboratory studies;
purity may vary (often 70–90 %). Suitable for self‑administration only in jurisdictions that allow it.
Pharmaceutical‑grade – Manufactured under GMP conditions, ensuring >98 % purity.
Typically available through licensed medical providers and carry
a prescription.
Choosing pharmaceutical‑grade material reduces contamination risk and ensures consistent potency.
What’s it like to use CJC‑1295 and ipamorelin?
Users report a noticeable increase in energy levels within days, followed by gradual improvements in sleep
quality and muscle tone. Side effects are mild: occasional flushing
or tingling at injection sites. Long‑term adherence
depends on clear goals and regular monitoring.
—
Preliminary and ongoing lab tests
Hormone panels – Baseline GH, IGF‑1, prolactin, cortisol levels
should be checked before starting therapy.
Metabolic profiling – Glucose tolerance tests to monitor insulin sensitivity.
Periodic imaging – Bone density scans for long‑term users
concerned about osteoporosis.
Reconstitution in bacteriostatic water (0.9 % saline) yields a concentration of ~1 mg/mL for both peptides.
Administer subcutaneously using insulin syringes.
—
Treatment protocol
Week 0–2 – Start with low doses to assess tolerance.
Month 3 onward – Evaluate IGF‑1 levels; adjust if necessary.
Maintenance – Continue once‑weekly CJC‑1295 with nightly Ipamorelin, or
taper as desired.
Storage
Keep peptides refrigerated (2–8 °C). Once
reconstituted, store in a cool, dark place and
use within 7 days to avoid degradation. Avoid repeated freeze–thaw cycles.
—
Who’s a candidate for CJC‑1295 and ipamorelin?
Adults aged 30–60 seeking anti‑aging or performance enhancement.
Individuals with documented GH deficiency (under medical supervision).
Who’s not a candidate for CJC‑1295 and ipamorelin?
Pregnant or nursing women.
Individuals with untreated thyroid disorders or hormone-sensitive cancers.
Those with severe cardiovascular disease without physician clearance.
People on medications that interact with GH pathways (e.g., corticosteroids) unless supervised.
Where to find CJC‑1295 and ipamorelin
Purchase from certified peptide distributors that provide certificates
of analysis, GMP compliance statements, and transparent
shipping policies. Verify the seller’s reputation through
peer reviews or industry forums before finalizing a transaction.
Anavar (Oxandrolone) is prized in bodybuilding circles for its ability
to add lean muscle mass, increase strength, and improve recovery while keeping water retention low.
The key to harnessing these benefits lies in precise dosing
tailored to the user’s goals—whether it’s a body recomposition, a prep
for competition, or simply enhancing everyday training performance.
—
Anavar Cycle Dosage for Men: Precision Dosing for Performance, Physique, and Safety
Unlike many anabolic steroids that rely on high megadoses to produce noticeable changes, Anavar is effective
at relatively low doses. A well‑structured cycle ensures optimal results while minimizing risk.
The dosage range typically spans 20 mg to 80 mg per
day, divided into tiers that align with distinct training objectives:
Entry‑Level / Body Recomp Phase – 20–30 mg/day
Lean Mass or Power Recomp Phase – 40–60 mg/day
Pre‑Contest Cycle or Strength Surge Phase – 60–80 mg/day
Each tier demands a different cycle length, post‑cycle therapy (PCT), and
potential stacking partners.
🔬 The Science Behind Anavar’s Uniqueness
Anavar is a synthetic derivative of dihydrotestosterone (DHT) with modifications that reduce its androgenic
activity while preserving anabolic potency. Key scientific points:
Selective Binding: Oxandrolone binds strongly to the androgen receptor but
exhibits lower affinity for enzymes that convert it into more potent, water‑retaining metabolites.
Low Aromatization: It does not aromatize into estrogen, eliminating typical estrogenic side effects such as gynecomastia and bloating.
Metabolic Stability: Its oral bioavailability is
high (≈90 %), allowing for consistent plasma levels with daily dosing.
These properties make Anavar a staple for users who need anabolic
benefits without the accompanying water weight or hormonal imbalance.
✅ Anavar Dosage for Men: Tiered by Purpose and Physique
The dosage selection depends on training phase, experience level,
and body composition goals. Below is an expanded view of each
tier:
🟢 20–30 mg/day (Entry‑Level / Body Recomp Phase)
Ideal For: New users, those recovering from injury, or individuals focused on fat loss
while preserving muscle.
Cycle Length: 6–8 weeks
Expected Gains: 2–4 lb of lean mass; modest strength increases.
Post‑Cycle Therapy: Mild PCT (e.g., clomiphene
50 mg daily for 4 weeks) if desired.
🟡 40–60 mg/day (Lean Mass or Power Recomp Phase)
Ideal For: Intermediate users seeking a noticeable boost
in muscle density and strength without significant water retention.
Cycle Length: 8–10 weeks
Expected Gains: 4–6 lb of lean mass; 15–25 % increase in bench/leg press.
Post‑Cycle Therapy: Standard PCT (clomiphene
or tamoxifen) for 4–5 weeks.
🔴 60–80 mg/day (Pre‑Contest Cycle or Strength Surge Phase)
Ideal For: Advanced athletes preparing for a competition or aiming for maximum strength output.
Cycle Length: 8–12 weeks
Expected Gains: 6–10 lb of lean mass; significant power gains.
Post‑Cycle Therapy: Robust PCT (clomiphene + anastrozole
if necessary) for 5–6 weeks.
🧠 Anavar Timing and Administration: Beyond “Just Take It”
While many users simply split doses, advanced timing can enhance efficacy:
Morning Dose – 10–15 mg to kickstart the day’s metabolism.
Mid‑Day Dose – 5–10 mg during lunch to maintain steady levels.
Evening Dose – Remaining dose before bed to aid recovery.
Taking Anavar with food or a small carbohydrate source can improve absorption and reduce gastrointestinal irritation. Additionally, pairing with an amino acid supplement like L‑Glutamine supports muscle repair during the night.
⚠️ Side Effects Are Dose and Context Dependent
Anavar’s side effect profile is milder than many steroids,
yet vigilance remains essential:
Androgenic Effects: Hair loss or acne may appear at higher doses (60–80 mg/day) especially in genetically predisposed
individuals.
Liver Stress: Oral administration can strain hepatic enzymes; liver
function tests are recommended every 4 weeks during a cycle above 40 mg/day.
Cardiovascular Impact: LDL cholesterol may rise while HDL drops.
A lipid panel pre‑ and post‑cycle is prudent.
Mood Changes: Some users report irritability or mood swings;
maintaining proper sleep and nutrition mitigates
this risk.
💡 Anavar and Stack Synergies (Performance‑Driven)
When used in combination with other compounds, Anavar can amplify results:
This plan balances muscle gain, strength increase,
and minimal water retention. Adjustments should be made based on individual response.
—
🧬 Anavar Cycle Dosage for Men
The overarching principle is to match the dose to the user’s
phase:
Recomposition: 20–30 mg/day
Lean Muscle Gain: 40–60 mg/day
Competition Prep/Power Surge: 60–80 mg/day
Always pair a cycle with proper nutrition, adequate protein intake (1.2–1.5 g/kg), and structured
training.
Final Take: Dose With Purpose, Not Ego
Anavar is powerful but not infinite. Responsible dosing—underpinned by clear objectives—yields the best balance
of muscle growth, strength, and safety. Avoiding over‑dosage preserves long‑term health while
still achieving impressive results in a relatively short time
frame.
Does Anavar Cause Gyno? Expert Advice For Steroid Users
Short Answer:
Oxandrolone (Anavar) itself is a weak anabolic steroid with very little direct estrogenic activity, so
it rarely causes gynecomastia on its own. However, in some people it
can shift the hormonal balance—especially when combined with other substances or high doses—test e and dianabol cycle lead to mild breast tissue growth.
The risk is low but not zero, so monitoring and proper dosing are key.
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CJC‑1295 and Ipamorelin
CJC‑1295 is a synthetic analogue of growth hormone‑releasing hormone (GHRH), while Ipamorelin is a selective growth hormone
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CJC‑1295 (also known as Dalotide): A 29‑amino‑acid peptide that
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Ipamorelin: A pentapeptide (His‑Pro‑Trp‑Gly‑Leu) that selectively activates the
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Research‑grade vs. pharmaceutical‑grade CJC‑1295 and ipamorelin
Research‑grade – Produced for laboratory studies;
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Peptide Typical Dose Frequency
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Ipamorelin 200–300 µg Twice daily (pre‑bedtime & post‑breakfast)
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